Rentarou Aijou has it all: looks, intelligence, athletic skill, and popularity with peers and mentors alike. Unfortunately, none of these qualities help Rentarou with his love life. On the day of his middle school graduation, he is once again turned down by a girl he confesses to, earning his one-hundredth rejection in a row. Down on his luck, he goes to a matchmaking shrine and wishes to finally get a girlfriend in high school. When the god of the shrine suddenly appears before him, Rentarou is told he will meet an astronomical total of one hundred soulmates in high school. Though Rentarou initially does not take this foretelling seriously, his doubts disappear when, on the first day of school, he meets two of these soulmates—Hakari Hanazono and Karane Inda—who both confess to him. With fated encounters and love confessions galore, Rentarou's life is about to get a lot more exciting.

After graduating from high school, Natsuko Hirose starts her career as an animator. Her talent quickly flourishes, and she makes her debut as a director in no time. Her first anime becomes a massive hit, sparking a social phenomenon and earning her recognition as an up-and-coming genius director. Her next project is set to be a romantic comedy movie themed around first love! However, having never been in love herself, Natsuko struggles to understand the concept of first love, and as a result, she's unable to create the storyboard, causing the movie production to come to a standstill.

The second season takes place directly after the events of the first season and picks up with Sung Jinwoo embracing his newfound powers as the Shadow Monarch. While he keeps his new powers a secret from people around him, a strange hunter who has been lost for nearly ten years returns with a dire warning of an upcoming catastrophe.

After saving the world from the destructive might of Majin Buu, Gokuu Son and his allies look forward to a well-earned rest. However, unbeknownst to them, their battle was recorded and observed by Gomah, an evil being who assumes the title of King in the Demon Realm, filling the void left behind with the death of former ruler Dabura. At Gomah's side is Degesu, the younger brother of Higashi no Kaioshin, a being who lords over the universe. Jealous of his brother's power, Degesu works alongside Gomah to steal Earth's Dragon Balls and preemptively subdue any potential future enemies. Calling upon the power of the legendary dragon Shenron, Gomah wishes for Gokuu and his friends to be reverted into children, intending to rob them of the limitless power that defeated Buu. With Earth's greatest warriors shrunken down, Gomah abducts Dende, the planet's acting god. But Gokuu refuses to be set back by his new body, working to master his younger form to fight as proficiently as he could as an adult. Joined by Kaioshin and Glorio—a mysterious but seemingly rebellious demon—Gokuu pursues Gomah to the Demon Realm in order to rescue Dende and restore his friends to their natural ages.

High school student Saito Houjo has married his classmate, Akane Sakuramori, the girl who is his biggest rival at school. The two can't seem to get along with each other, but their heart-pounding newlywed life is about to begin!